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Ou, J., Smith, R

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(146) observed significant blood-to-brain influx for non-acylated GLP-1 mimetics like exendin-4 and lixisenatide, whereas acylated GLP-1 analogues such as liraglutide and semaglutide showed minimal blood-brain barrier penetration in mice

This medication can be used to manage nausea and vomiting in patients who have been prescribed GLP-1 treatments during the initiation phase, or after a dose increase, when these symptoms can be at their worst

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